解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:The goal of this study is to characterize the phenomenon of evoked tactile sensation (ETS) on the stump skin of forearm amputees using transcutaneous electrical nerve stimulation (TENS). APPROACH:We identified the projected finger map (PFM) of ETS on the stump skin in 11 forearm amputees, and compared percep...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066002
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The various parameters that define a hand movement such as its trajectory, speed, etc, are encoded in distinct brain activities. Decoding this information from neurophysiological recordings is a less explored area of brain-computer interface (BCI) research. Applying non-invasive recordings such as electroence...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066019
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:We consider the problem of optimal probing to learn connections in an evoked dynamic network. Such a network, in which each edge measures an input-output relationship between sites in sensor/actuator-space, is relevant to emerging applications in neural mapping and neural connectivity estimation. APPROACH:We...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066011
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The majority of near-infrared spectroscopy (NIRS) brain-computer interface (BCI) studies have investigated binary classification problems. Limited work has considered differentiation of more than two mental states, or multi-class differentiation of higher-level cognitive tasks using measurements outside of th...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/6/066008
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Although electrode size should be miniaturized to provide higher selectivity for neural signal recording and to avoid tissue damage, small sized electrodes induce high impedance, which decreases recording quality. In this work, the electrode surface was modified to increase the effective surface area to lower...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/5/056018
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Wireless control and power harvesting systems that operate injectable, cellular-scale optoelectronic components provide important demonstrated capabilities in neuromodulatory techniques such as optogenetics. Here, we report a radio frequency (RF) control/harvesting device that offers dramatically reduced size...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/5/056002
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Two-dimensional (2D) movement control is an important issue in brain-computer interfaces (BCIs) research because being able to move, for example, a cursor with the brain will enable patients with motor disabilities to control their environment. However, it is still a challenge to continuously control 2D movem...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/4/046021
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:One of the main goals of brain-machine interface (BMI) research is to restore function to people with paralysis. Currently, multiple BMI design features are being investigated, based on various input modalities (externally applied and surgically implantable sensors) and output modalities (e.g. control of comp...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/4/043002
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees. APPROACH:Multi-contact cuff electrode...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/2/026002
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The human auditory system acquires environmental information under sound stimuli faster than visual or touch systems, which in turn, allows for faster human responses to such stimuli. It also complements senses such as sight, where direct line-of-view is necessary to identify objects, in the environment recog...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/1/016012
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:In a previous study we demonstrated continuous translation, orientation and one-dimensional grasping control of a prosthetic limb (seven degrees of freedom) by a human subject with tetraplegia using a brain-machine interface (BMI). The current study, in the same subject, immediately followed the previous work...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/1/016011
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:For intracortical brain-machine interfaces (BMIs), action potential voltage waveforms are often sorted to separate out individual neurons. If these neurons contain independent tuning information, this process could increase BMI performance. However, the sorting of action potentials ('spikes') requires high sa...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/12/1/016009
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:We propose a new hybrid brain-computer interface (BCI) system that integrates two different EEG tasks: tactile selective attention (TSA) using a vibro-tactile stimulator on the left/right finger and motor imagery (MI) of left/right hand movement. Event-related desynchronization (ERD) from the MI task and stea...
journal_title:Journal of neural engineering
pub_type: 杂志文章,随机对照试验
doi:10.1088/1741-2560/11/6/066004
更新日期:2014-12-01 00:00:00
abstract::This paper presents a wheelchair navigation system based on a hidden Markov model (HMM), which we developed to assist those with restricted mobility. The semi-autonomous system is equipped with obstacle/collision avoidance sensors and it takes the electrooculography (EOG) signal traces from the user as commands to man...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/5/056018
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Powered robotic prostheses create a need for natural-feeling user interfaces and robust control schemes. Here, we examined the ability of a nonlinear autoregressive model to continuously map the kinematics of a transtibial prosthesis and electromyographic (EMG) activity recorded within socket to the future es...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/5/056027
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:The fact that all human action is preceded by brain processes partially observable through neuroimaging devices such as electroencephalography (EEG) is currently being explored in a number of applications. A recent study by Haufe et al (2011 J. Neural Eng. 8 056001) demonstrates the possibility of performing ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/5/056011
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Brain-computer interfaces (BCIs) have the potential to be valuable clinical tools. However, the varied nature of BCIs, combined with the large number of laboratories participating in BCI research, makes uniform performance reporting difficult. To address this situation, we present a tutorial on performance me...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/3/035001
更新日期:2014-06-01 00:00:00
abstract::After extended implantation times, traditional intracortical neural probes exhibit a foreign-body reaction characterized by a reactive glial sheath that has been associated with increased system impedance and signal deterioration. Previously, we have proposed that the local in vivo polymerization of an electronically ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/2/026005
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Analysis of intra- and perioperatively recorded cortical and basal ganglia local field potentials in human movement disorders has provided great insight into the pathophysiology of diseases such as Parkinson's, dystonia, and essential tremor. However, in order to better understand the network abnormalities an...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/1/016009
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:A signal-based metric for assessment of accuracy of motor unit (MU) identification from high-density surface electromyograms (EMG) is introduced. This metric, so-called pulse-to-noise-ratio (PNR), is computationally efficient, does not require any additional experimental costs and can be applied to every MU t...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/11/1/016008
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:Analyzing and interpreting the activity of a heterogeneous population of neurons can be challenging, especially as the number of neurons, experimental trials, and experimental conditions increases. One approach is to extract a set of latent variables that succinctly captures the prominent co-fluctuation patte...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066012
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Most recent steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems have used a single frequency for each target, so that a large number of targets require a large number of stimulus frequencies and therefore a wider frequency band. However, human beings show good SSVEP respo...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066009
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Brain-computer interfaces (BCIs) are confronted with two fundamental challenges: (a) the uncertainty associated with decoding noisy brain signals, and (b) the need for co-adaptation between the brain and the interface so as to cooperatively achieve a common goal in a task. We seek to mitigate these challenges...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/6/066008
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. APPROACH:This study presents a novel signal processing technique to extract features from non-...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/5/056018
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:The past two decades have seen dramatic progress in our ability to model brain signals recorded by electroencephalography, functional near-infrared spectroscopy, etc., and to derive real-time estimates of user cognitive state, response, or intent for a variety of purposes: to restore communication by the seve...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/5/056014
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Multiresolution analysis (MRA) offers a useful framework for signal analysis in the temporal and spectral domains, although commonly employed MRA methods may not be the best approach for brain computer interface (BCI) applications. This study aims to develop a new MRA system for extracting tempo-spatial-spect...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/046014
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:Previous studies have shown that single-frequency impedance measurements could provide useful information about the distance between the neuroprosthesis and the retina. This work investigates the use of impedance spectroscopy in monitoring subretinal implantations of flexible micro-electrode arrays and focuse...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/046002
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:Reliable chronic recordings from implanted neural probes remain a significant challenge; current silicon-based and microwire technologies experience a wide range of biotic and abiotic failure modes contributing to loss of signal quality. APPROACH:A multi-prong alternative strategy with potential to overcome ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/4/045002
更新日期:2013-08-01 00:00:00
abstract::Corrosion is a prime concern for active implantable devices. In this paper we review the principles underlying the concepts of hermetic packages and encapsulation, used to protect implanted electronics, some of which remain widely overlooked. We discuss how technological advances have created a need to update the way ...
journal_title:Journal of neural engineering
pub_type: 杂志文章,评审
doi:10.1088/1741-2560/10/3/031002
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:High-rate pulse trains have proven to be effective in cochlear prosthetics and, more recently, have been shown to elicit a wide range of interesting response properties in axons of the peripheral nervous system. Surprisingly, the effectiveness of such trains for use in retinal prostheses has not been explored...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/3/036009
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:A major difficulty of brain-computer interface (BCI) technology is dealing with the noise of EEG and its signal variations. Previous works studied time-dependent non-stationarities for BCIs in which the user's mental task was independent of the device operation (e.g., the mental task was motor imagery and the...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/2/026024
更新日期:2013-04-01 00:00:00
abstract:UNLABELLED:Transcranial Doppler (TCD) was recently introduced as a new brain-computer interface (BCI) modality for detecting task-induced hemispheric lateralization. To date, single-trial discrimination between a lateralized mental activity and a rest state has been demonstrated with long (45 s) activation time periods...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/10/1/016005
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Brains, like other physical devices, are inherently noisy. This source of variability is large, to the extent that internal noise often impacts human sensory processing more than externally induced (stimulus-driven) perturbations. Despite the fundamental nature of this phenomenon, its statistical distribution...
journal_title:Journal of neural engineering
pub_type: 杂志文章,随机对照试验
doi:10.1088/1741-2560/10/1/016014
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:Penetrating cortical neural probe technologies allow investigators to record electrical signals in the brain. Implantation of probes results in acute tissue damage, and microglia density increases around implanted devices over weeks. However, the mechanisms underlying this encapsulation are not well understoo...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/6/066001
更新日期:2012-12-01 00:00:00
abstract::Chronic motor cortex stimulation (MCS) is currently being investigated as a treatment method for Parkinson's disease (PD). Unfortunately, the underlying mechanisms of this treatment are unclear and there are many uncertainties regarding the most effective stimulation parameters and electrode configuration. In this pap...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/5/056005
更新日期:2012-10-01 00:00:00
abstract::Functional mapping of eloquent cortex is a common and necessary component of neurosurgical operative planning. Current electrical stimulation-based techniques are inefficient, can evoke seizures and are prone to false-negative results. Here, we present a novel cortical mapping system that extracts event-related neural...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/4/046018
更新日期:2012-08-01 00:00:00
abstract::One of the most important stages in a brain-computer interface (BCI) system is that of extracting features that can reliably discriminate data recorded during different user states. A popular technique used for feature extraction in BCIs is the common spatial patterns (CSP) method, which provides a set of spatial filt...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/4/045009
更新日期:2012-08-01 00:00:00
abstract::The aim of this paper is to use recent advances in the clinical understanding of the temporal evolution of seizure burden in neonates with hypoxic ischemic encephalopathy to improve the performance of automated detection algorithms. Probabilistic weights are designed from temporal locations of neonatal seizure events ...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/4/046002
更新日期:2012-08-01 00:00:00
abstract::The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring sight to patients blinded by degenerative retinal diseases. A silicon photodiode array for subretinal stimulation has been fabricated by a silicon-integrated-circuit/MEMS process. Each pixel in the two-dimensional array c...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/4/046014
更新日期:2012-08-01 00:00:00
abstract::Hybrid electro-optical neural stimulation is a novel paradigm combining the advantages of optical and electrical stimulation techniques while reducing their respective limitations. However, in order to fulfill its promise, this technique requires reduced variability and improved reproducibility. Here we used a compara...
journal_title:Journal of neural engineering
pub_type: 杂志文章
doi:10.1088/1741-2560/9/3/036003
更新日期:2012-06-01 00:00:00